Anti-EGFR Recombinant Antibody (Nimotuzumab)
CAT#: TAB-710
Recombinant humanized (from mouse) antibody expressed in CHO binding to human EGFR. Nimotuzumab is a humanized monoclonal antibody that as of 2014 had orphan status in the US and EU for glioma, and marketing approval in India, China, and other countries for squamous cell carcinomas of the head and neck.
Published Data
Tested Data
Gene Expression
Figure 1 EGFR signal transduction and effects of EGFR inhibition on downstream targets.
Scheme of EGFR signal transduction. Nimotuzumab and PD153035 are inhibitors of EGFR: Activation of EGFR results in activation of Akt signaling which relieves a TSC1/TSC2 as well as PRAS40 (via phosphorylation of Thr246)-mediated inhibition of mTORC1. RPS6 phosphorylation at Ser235/236 and Ser 240/244 is regulated by mTORC1.
Ronellenfitsch, M. W., Zeiner, P. S., Mittelbronn, M., Urban, H., Pietsch, T., Reuter, D., ... & Harter, P. N. (2018). Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma. Acta neuropathologica communications, 6(1), 81.
Figure 2 EGFR signal transduction and effects of EGFR inhibition on downstream targets.
LNT-229 cells were incubated in serum-free DMEM for 90 min with vehicle (DMSO control), PD153035 (dissolved in DMSO), control solution for nimotuzumab (placebo solution of the trial) or 1 ?M nimotuzumab as indicated. Cellular lysates were analyzed by immunoblot with antibodies as indicated.
Ronellenfitsch, M. W., Zeiner, P. S., Mittelbronn, M., Urban, H., Pietsch, T., Reuter, D., ... & Harter, P. N. (2018). Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma. Acta neuropathologica communications, 6(1), 81.
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WB
Figure 1 Anti-EGFR Recombinant Antibody (TAB-710) in WB
Western blot analysis of TAB-710 was performed with human EGFR protein (His Tag).
TAB-710 incubation concentration: 2 ng/μL.
The secondary antibody: HRP-anti-human IgG
Lane 1: Reducing Antigen (0.1 μg)
Lane 2: Reducing Antigen (0.3 μg)
Lane 3: Reducing Antigen (0.6 μg)
ELISA
Figure 2 Anti-EGFR Recombinant Antibody (TAB-710) in ELISA
ELISA analysis of TAB-710 was performed by coating with human EGFR protein (His Tag).
The secondary antibody: HRP-anti-human IgG
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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cell junctions.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/144_E9_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/143_E9_1_blue_red_green.jpg
Normal Tissue
Figure 3 Colon
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Bowman's capsule
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Collecting ducts
Staining:Medium
Intensity: Strong
Quantity: <25%
Distal tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Pachytene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Round or early spermatids
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_6_6.jpg
Normal Tissue
Figure 7 Placenta
Cytotrophoblasts
Staining:High
Intensity: Strong
Quantity:>75%
Decidual cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Hofbauer cells
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining:High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_1_7.jpg
Normal Tissue
Figure 8 Lymph node
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enriched (A-431)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000146648-EGFR
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- IgG1 - kappa
- Species Reactivity
- Human
- Applications
- ELISA, IP, FC, FuncS, Neut, IF, IHC
- Trade name
- TheraCIM
- CAS
- 780758-10-3
- Generic Name
- nimotuzumab
- Biological Half-Life
- 62–304 hours
- ATC Code
- L01XC
- MW
- 147,659.45 g/mol
- Related Disease
- Glioma cancers
Product Property
- Purity
- >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
- Storage
- Store at -20°C. Avoid multiple freeze/thaw cycles.
Applications
- Application Notes
- The EGFR antibody has been reported in applications of Activ, WB.
Target
- Alternative Names
- nimotuzumab;TheraCIM;780758-10-3;hR3;h-R3;TheraCIM;BIOMAb EGFR;TheraCIM;Theraloc;CIMAher;EGFR;epidermal growth factor receptor;epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) , ERBB;ERBB1;erythroblastic le
- Gene ID
- 1956
- UniProt ID
- P00533
REVIEWS AND Q&AS
CITATIONS
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Customer Review
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Reliable and Sturdy
The antibody has a long shelf life and is stable for months. The lot I've been using for various experiments is still operating just as it did when it was initially used.
Easy to Use
This antibody comes with a detailed how-to instruction and is easy to use. Every sample I tested had assays run on it, and the outcomes are repeatable and highly consistent.
Affordable and Useful
This antibody is really inexpensive when you take into account its high quality and performance. It exceeded all of my expectations in a variety of research applications. Very strongly suggested!
Q&As
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Can this antibody detect low-abundance proteins?
A: Yes, but it may require optimizing assay conditions, increasing sample volume, or using high-sensitivity detection methods to improve signal.
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How do I choose the right lysis buffer for my samples?
A: The choice of lysis buffer depends on your target protein's localization and characteristics. For example, RIPA buffer is suitable for cytoplasmic and nuclear proteins.
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How do I know if the antibody reagent is contaminated?
A: Signs of contamination include cloudiness, precipitates, or unusual results in your assays. It's crucial to use aseptic techniques and aliquot into sterile containers.
View the frequently asked questions answered by Creative Biolabs Support.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-710, RRID: AB_3111988)
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Biosimilar Overview
Please refer to Nimotuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Nimotuzumab.
Related Diseases
Bladder Cancer
Non-small Cell Lung Cancer
Pancreatic Cancer
Hepatocellular Carcinoma
Cushing Syndrome
Related Signaling Pathways
JAK-STAT Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Nimotuzumab"
Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-710)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized (from mouse) antibody expressed in CHO binding to human EGFR. It is a humanized monoclonal antibody.
DrugMonitor™ Anti-Nimotuzumab Antibody (VS-1224-YC808)Nimotuzumab (h-R3), a humanized monoclonal antibody targeting EGFR, has shown promising efficacy combined with radiation in several cancer types, meriting further investigation. The DrugMonitor™ Anti-Nimotuzumab Antibody (VS-1224-YC808) is an anti-drug antibody (ADA) against Nimotuzumab. This drug-based antibody is raised in mice immunized with the Nimotuzumab. The anti-Nimotuzumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Nimotuzumab in samples.
See other products for "EGFR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1078z | Mouse Anti-EGFR Recombinant Antibody (clone 42C11) | WB, ELISA, FC, IF, IHC, FuncS | Mouse IgG1, κ |
| PABL-462 | Human Anti-EGFR Recombinant Antibody (clone C225) | FC | Human IgG |
| PABL-463 | Human Anti-EGFR Recombinant Antibody (PABL-463) | ELISA, WB, FuncS | Humanized IgG |
| TAB-477CQ | Human Anti-EGFR Recombinant Antibody (clone Laprituximab) | ELISA, IHC, FC, IP, IF, WB | Chimeric (mouse/human) IgG1, κ |
| MOB-052LC | Mouse Anti-EGFR Recombinant Antibody (clone 7H7) | WB, IP | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-228CL | Anti-Human EGFR Recombinant Antibody (ABT-806) | WB, IHC | Antibody |
| TAB-274MZ-F(E) | Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-274MZ-F(E)) | FC | Humanized Fab |
| TAB-297MZ-F(E) | Anti-Human EGFR Recombinant Antibody Fab Fragment (H225) | ELISA, WB | Humanized antibody |
| TAB-298MZ-F(E) | Anti-Human EGFR Recombinant Antibody Fab Fragment (Hu225) | ELISA, WB | Humanized antibody |
| TAB-300MZ-F(E) | Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-300MZ-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBZ-039 | Mouse Anti-EGFR Recombinant Antibody (clone mAb528); scFv Fragment | FC | Mouse scFv |
| PSBW-039 | Mouse Anti-EGFR Recombinant Antibody scFv Fragment (PSBW-039) | Block | Mouse scFv |
| PSBC-040 | Human Anti-EGFR Recombinant Antibody (clone MR1); scFv Fragment | Block | Human scFv |
| HPAB-2194LY-S(P) | Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (HPAB-2194LY-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-2195LY-S(P) | Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (HPAB-2195LY-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBW-171 | Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (PSBW-171) | WB | Mouse scFv |
| HPAB-0161CQ-F(E) | Human Anti-EGFR Recombinant Antibody; Fab Fragment (HPAB-0161CQ-F(E)) | ELISA, FC, IHC | Human Fab |
| HPAB-2194LY-F(E) | Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (HPAB-2194LY-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-2195LY-F(E) | Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (HPAB-2195LY-F(E)) | ELISA | Mouse Fab |
| HPAB-2196LY-F(E) | Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (HPAB-2196LY-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0225CL | Human Anti-EGFR Recombinant Antibody (TAB-0225CL) | Block, Inhib, FuncS, Apop, In vivo | Chimeric (Mouse/Human) IgG1 |
| TAB-0225CL-F(E) | Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-0225CL-F(E)) | Block, Inhib, FuncS, Apop, In vivo | Chimeric (Mouse/Human) Fab |
| TAB-302MZ | Human Anti-EGFR Recombinant Antibody (TAB-302MZ) | ELISA | Chimeric (mouse/human) IgG1 |
| TAB-308MZ | Human Anti-EGFR Recombinant Antibody (TAB-308MZ) | FuncS | Chimeric antibody (mouse/human) |
| TAB-464CQ | Anti-Human EGFR Recombinant Antibody (TAB-464CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0564CL-F(E) | Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-0564CL-F(E)) | ELISA | Mouse Fab |
| TAB-0565CL-F(E) | Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-0565CL-F(E)) | ELISA | Mouse Fab |
| TAB-273MZ-F(E) | Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-273MZ-F(E)) | FC | Mouse Fab |
| TAB-275MZ-F(E) | Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-275MZ-F(E)) | FC | Mouse Fab |
| TAB-276MZ-F(E) | Anti-Human EGFR Recombinant Antibody Fab Fragment (LA1) | MTT assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-270MZ | Human Anti-EGFR Recombinant Antibody (TAB-270MZ) | ELISA | Human antibody |
| TAB-278MZ | Human Anti-EGFR Recombinant Antibody (TAB-278MZ) | Cyt, ELISA, Inhib | Human IgG |
| TAB-279MZ | Human Anti-EGFR Recombinant Antibody (TAB-279MZ) | Cyt, ELISA, Inhib | Human IgG |
| TAB-282MZ | Human Anti-EGFR Recombinant Antibody (TAB-282MZ) | Cyt, FuncS, Inhib | Human IgG |
| TAB-283MZ | Human Anti-EGFR Recombinant Antibody (TAB-283MZ) | Cyt, FuncS, Inhib | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-055LC | Recombinant Anti-Human EGFR Antibody (Fc glycosylation/High-mannose glycosylated) | ELISA | Chimeric antibody (mouse/human) |
| Gly-144LC | Recombinant Anti-Human EGFR Antibody (Fc glycosylation) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-055LC-1 | Recombinant Anti-Human EGFR Antibody (Fc glycosylation/High-mannose glycosylated) | ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-167LC | Recombinant Anti-Human EGFR Antibody (Non-glycosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0183MZ | Chicken Anti-EGFR Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC773 | A*0201/Human EGFR (YLNTVQPTCV) MHC Tetramer | FCM | |
| MHC-LC4545 | PE-DQB1*03:02/Human EGFR (SRALEEKKGNYVVTHG) MHC Tetramer | FCM | |
| MHC-YF409 | A*02:01/Human EGF-R-479 (KLFGTSGQKT) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-722CQ | Rabbit Anti-EGFR Recombinant Antibody (clone CBL1011) | Neut | Rabbit IgG |
| NEUT-723CQ | Mouse Anti-EGFR Recombinant Antibody (clone CBL931) | WB, IP, IHC, ICC, Neut | Mouse IgG1 |
| NEUT-724CQ | Rabbit Anti-EGFR Recombinant Antibody (NEUT-724CQ) | IF, FC, WB, IP, Neut | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1101 | Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone DS1101AB) | IHC-P | Rabbit IgG |
| MOR-4570 | Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH82DS) | ELISA | Rabbit IgG |
| MOR-4571 | Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH83DS) | WB, IF, ICC, FC | Rabbit IgG |
| MOR-4675 | Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH189DS) | WB, IF, ICC, FC | Rabbit IgG |
| MOR-0033-FY | Rabbit Anti-EGFR Recombinant Antibody (clone AFY0004) | ICC, IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-165 | Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-165) | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
| AFC-TAB-464CQ | Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-464CQ) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-003 | Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-003) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-040 | Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-040) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-119 | Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-119) | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP881-YC | Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP881-YC) | ELISA, FC, IP, FuncS | Llama VHH |
| HPAB-AP882-YC | Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP882-YC) | ELISA | Llama VHH |
| HPAB-AP883-YC | Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP883-YC) | ELISA | Llama VHH |
| HPAB-AP884-YC | Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP884-YC) | ELISA | Llama VHH |
| HPAB-AP885-YC | Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP885-YC) | ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY84 | AbPlus™ Anti-EGFR Magnetic Beads (pSEX81-6) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC32 | Mouse Anti-EGFR Recombinant Antibody (VS-0924-YC32) - Cancer Stem Cell Marker | IHC, WB | Mouse IgG1 |
| VS-0924-YC35 | Rabbit Anti-EGFR Antibody (VS-0924-YC35) - Cancer Stem Cell Marker | IHC, WB, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY177 | Mouse Anti-NHP EGFR Recombinant Antibody (clone 225) | IF, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY28 | Human Anti-EGFR (clone ABT-806) scFv-Fc Chimera | FC, Cyt | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY102 | CytoStream™ Mouse Anti-EGFR Recombinant Antibody (VS-0225-XY102) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY735 | Anti-EGFR Immunohistochemistry Kit | IHC | |
| VS-0525-XY2183 | Anti-Mouse EGFR Immunohistochemistry Kit | IHC | |
| VS-0525-XY2182 | Anti-Human EGFR Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC340 | Recombinant Anti-EGFR Vesicular Antibody, EV Displayed (VS-0425-YC340) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC65 | Recombinant Anti-EGFR (AA 269-278 x AA 526-535) Biparatopic Antibody, Tandem scFv (Clone Pep 2 x Clone Pep 3) | FC | Tandem scFv |
| VS-0525-YC66 | Recombinant Anti-EGFR (AA 582-591 x AA 606-614) Biparatopic Antibody, Tandem scFv (Clone Pep 4 x Clone Pep 1) | FC | Tandem scFv |
| VS-0525-YC68 | Recombinant Anti-EGFR (AA 526-535 x AA 600-605) Biparatopic Antibody, Tandem scFv (Clone Pep 3 x Clone Pep 5) | FC | Tandem scFv |
| VS-0525-YC213 | Recombinant Anti-EGFR (Domain II x Domain III) Biparatopic Antibody, Tandem scFv | ELISA, FC, IF, IHC, IP | Tandem scFv |
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